Article
Viremic dissemination of mouse hepatitis virus-JHM following intranasal inoculation of mice.
Archives of virology - 1 Jan 1992
Barthold S W, Smith A L
Abstract excerpt
Using a sensitive infant mouse bioassay to detect infectious virus, the pattern of mouse hepatitis virus (MHV) JHM dissemination in blood and other tissues was examined during the first 5 days following intranasal inoculation. MHV replicated in nasal turbinates of both susceptible BALB and resistant SJL mice from days 1 through 5, but BALB mice had higher titers on days 1 and 2. Viremia was detectable on days 1...
Topics
- Animals
- Antibodies, Viral
- Chi-Square Distribution
- Genetic Predisposition to Disease
- Hepatitis, Viral, Animal
- Interferon-alpha
- Interferon-beta
- Kinetics
- Mice
- Mice, Inbred BALB C
- Murine hepatitis virus
