Article
In vitro splenic T cell responses of diverse mouse genotypes after oronasal exposure to mouse hepatitis virus, strain JHM.
Laboratory animal science - 1 Apr 1991
Smith A L, Winograd D F, de Souza M S
Abstract excerpt
Mortality rates among BALB/cByJ, A/JCr, C3H/HeSnJ, and C57BL/6NCr mice inoculated oronasally with mouse hepatitis virus (MHV) strain JHM, ranged from 25 to 67%. Spleen cells harvested from the first three genotypes at 5 days postinoculation proliferated poorly in response to concanavalin A stimul...
Topics
- Administration, Intranasal
- Administration, Oral
- Animals
- Cells, Cultured
- Concanavalin A
- Female
- Genotype
- Interleukin-2
- Interleukin-4
- Lymphocyte Activation
- Mice
- Mice, Inbred A
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Murine hepatitis virus
- Spleen
- T-Lymphocytes