Article
Interval mapping of quantitative trait loci using a sib-pair linkage method.
Genetic epidemiology - 1 Jan 1995
Borecki I B, Vogler G P
Abstract excerpt
Fulker and Cardon's interval mapping extension of Haseman and Elston's sib-pair linkage method was used to map loci affecting the quantitative phenotypes presented as part of Problem 2, both adjusted and not adjusted for covariates: Q1 was adjusted for age and the environmental factor (EF); Q2 and Q3 for EF; and Q4 for age, sex, and EF. Adjusted Q2 and Q4 were also log-transformed. The effect of candidate locus...
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