Article
Multipoint interval mapping of quantitative trait loci, using sib pairs.
American journal of human genetics - 1 May 1995
Fulker D W, Cherny S S, Cardon L R
Abstract excerpt
The sib-pair interval-mapping procedure of Fulker and Cardon is extended to take account of all available marker information on a chromosome simultaneously. The method provides a computationally fast multipoint analysis of sib-pair data, using a modified Haseman-Elston approach. It gives results very similar to those of the earlier interval-mapping procedure when marker information is relatively uniform and a...
Topics
- Alleles
- Chromosome Mapping
- Computer Simulation
- Genetic Markers
- Humans
- Models, Genetic
- Nuclear Family
- Statistics as Topic
- Time Factors
