Article
Analysis of quantitative trait loci.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008
Falchi Mario
Abstract excerpt
Diseases with complex inheritance are characterized by multiple genetic and environmental factors that often interact to produce clinical symptoms. In addition, etiological heterogeneity (different risk factors causing similar phenotypes) obscure the inheritance pattern among affected relatives and hamper the feasibility of gene-mapping studies. For such diseases, the careful selection of quantitative phenotypes...
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