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P21 codon 31 polymorphism associated with cancer among white people: evidence from a meta-analysis involving 78,074 subjects.

Mutagenesis - 1 Jul 2011

Liu Fei, Li Bo, Wei Yonggang, Chen Xi, Ma Yu, Yan Lvnan, Wen Tianfu

Abstract excerpt

p21 protein is a cell cycle regulator that induces G1 arrest, leading to DNA repair or apoptosis. Previous studies have shown that p21 polymorphism in codon 31 (Ser 31 Arg) may play a role in susceptibility to cancer. However, the results from the published studies are conflicting. To derive a more precise estimation of association between the p21 Ser31Arg polymorphism and risk of cancer, we performed a...

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PMID: 21415438
DOI: 10.1093/mutage/ger010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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