Article
Analysis of the p53 gene in human uterine carcinoma cell lines.
Cancer research - 15 Dec 1991
Yaginuma Y, Westphal H
Abstract excerpt
The inactivation of the tumor suppressor gene p53 has been demonstrated in a variety of human tumors. In this study, we present a p53 gene analysis of 13 uterine carcinoma cell lines. Sequencing analysis of the entire coding region revealed mutations changing the p53 amino acid composition in all...
Topics
- Base Sequence
- Blotting, Northern
- Carcinoma
- Female
- Gene Expression
- Genes, Tumor Suppressor
- Humans
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Papillomaviridae
- Polymerase Chain Reaction
- RNA, Messenger
- RNA, Neoplasm
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53
- Uterine Neoplasms
