Article
Association between p21 Ser31Arg polymorphism and cancer risk: a meta-analysis.
Chinese journal of cancer - 1 Apr 2011
Ma Hongxia, Zhou Ziyuan, Wei Sheng, Wei Qingyi
Abstract excerpt
P21 (CDKN1A), a key cell cycle regulatory protein that governs cell cycle progression from G1 to S phase, can regulate cell proliferation, growth arrest, and apoptosis. The Ser31Arg polymorphism is located in the highly conserved region of p21 and may encode functionally distinct proteins. Although many epidemiological studies have been conducted to evaluate the association between the p21 Ser31Arg polymorphism...
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