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Article

Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis.

Cancer science - 1 Aug 2006

Wang Hui-Ching, Huang Wenya, Lai Ming-Der, Su Ih-Jen

Abstract excerpt

Although hepatitis B virus (HBV) has been documented to cause hepatocellular carcinoma (HCC), the exact role of HBV in the development of HCC remains enigmatic. Several hypotheses have been proposed to explain the potential mechanism, including insertional mutagenesis of HBV genomes and transcriptional activators of HBV gene products such as hepatitis B x protein (HBx) and truncated middle S mutants. In the past...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16863502
DOI: 10.1111/j.1349-7006.2006.00235.x
PMCID: PMC11158693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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