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Article

Liver graft infection by HBV S-gene mutants in transplant patients receiving long-term HBIg prophylaxis.

Hepato-gastroenterology - 1 Jan 2000

Santantonio T, Gunther S, Sterneck M, Rendina M, Messner M, Launois B, Francavilla A, Pastore G, Will H

Abstract excerpt

BACKGROUND/AIMS: HBV reinfection of transplant livers occurs frequently even in the presence of high doses of anti-HBs immunoglobulins. We analyzed, retrospectively, whether and which type of S-gene variants were selected by long-term polyclonal anti-HBs (HBIg) treatment leading to reinfection of patients transplanted because of chronic HBs-positive end-stage liver disease. METHODOLOGY: The preS2/S gene of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10430358

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