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Article

Emergence of and takeover by hepatitis B virus (HBV) with rearrangements in the pre-S/S and pre-C/C genes during chronic HBV infection.

Journal of virology - 1 Jul 1991

Tran A, Kremsdorf D, Capel F, Housset C, Dauguet C, Petit M A, Brechot C

Abstract excerpt

We have shown, by analyzing serial serum samples from a chronic hepatitis B virus (HBV) carrier, the emergence of HBV DNA molecules with nucleotide rearrangements in the pre-S/S and pre-C/C genes. Serum samples were obtained at four different times (1983, 1985, 1988, and 1989) from an HBsAg- and HBeAg-positive carrier with chronic hepatitis. The polymerase chain reaction was used to amplify the pre-S/S and...

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Identifiers

PMID: 2041082
DOI: 10.1128/JVI.65.7.3566-3574.1991
PMCID: PMC241355

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