Article
Precore and contiguous regions of hepatitis B virus in liver transplantation for end-stage hepatitis B.
Gastroenterology - 1 Dec 1994
Laskus T, Rakela J, Steers J L, Wiesner R H, Persing D H
Abstract excerpt
BACKGROUND/AIMS: Recurrent hepatitis B virus (HBV) infection is the leading cause of mortality and morbidity after orthotopic liver transplantation (OLT) for HBV-related liver disease, but the extent of viral genetic variation in this setting remains unknown. METHODS: Eight patients who underwent OLT for HBV-related liver disease were studied; 7 had cirrhosis and 1 had fulminant hepatitis. Four patients received...
Topics
- Adult
- Base Sequence
- Codon
- DNA, Viral
- Female
- Gene Amplification
- Genetic Variation
- Hepatitis B
- Hepatitis B virus
- Humans
- Liver Transplantation
- Male
