Article

Evolutionary analysis of pre S/S mutations in HBeAg-negative chronic hepatitis B with HBsAg <100 IU/ml

2020-04-06

Abstract excerpt

<title>Abstract</title> <p>Background: Hepatitis B surface antigen (HBsAg) and viral load are important clinical indicators for patients with chronic hepatitis B (CHB) infection treated with antiviral therapy. Few studies have evaluated viral sequence biomarkers predicting the risk of hepatocellular carcinoma (HCC) in the stage, which show a low serological response (HBsAg <100 IU/ml) and high viral levels (HBV D...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f3615c4b-a644-5cff-8178-42e2624f845c
DOI: 10.21203/rs.3.rs-20997/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evolutionary analysis of pre S/S mutations in HBeAg-negative chronic hepatitis B with HBsAg <100 IU/mlDOI 10.21203/rs.3.rs-20997/v1Read

Evolutionary Analysis of Pre-S/S Mutations in HBeAg-Negative Chronic Hepatitis B With HBsAg < 100 IU/ml.Semantic proximity Read

Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until NowSemantic proximity Read

Do the circulating Pre-S/S quasispecies influence hepatitis B virus surface antigen levels in the HBeAg negative phase of HBV infection?Semantic proximity Read

Hepatitis B virus pre-S/S variants in liver diseases.Semantic proximity Read

Sequence analysis of the Pre-S gene in chronic asymptomatic HBV carriers with low-level HBsAg.Semantic proximity Read

Prevalence and significance of hepatitis B virus (HBV) pre-S mutants in serum and liver at different replicative stages of chronic HBV infection.Semantic proximity Read

The Impact of HBV Quasispecies Features on Immune Status in HBsAg+/HBsAb+ Patients With HBV Genotype C Using Next-Generation Sequencing.Semantic proximity Read

Prevalence of S gene mutations within the major hydrophilic region of hepatitis B virus in patients in Dongguan, southern China.Semantic proximity Read

A strong conservative tendency in HBV transcriptase (RT): a majority of natural RT mutations derived from the S gene.Semantic proximity Read

Naturally occurring pre-S mutations promote occult HBV infection by affecting pre-S2/S promoter activity.Semantic proximity Read

Evolutionary Changes of Hepatitis B Virus Pre-S Mutations Prior to Development of Hepatocellular Carcinoma.Semantic proximity Read

Comparison of S gene mutations in patients with occult and chronic hepatitis B virus infection.Semantic proximity Read