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APC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structures

28 Mar 2019

Abstract excerpt

Hepatoblastoma (HB) is the most common liver cancer in children. We aimed to characterize HB related to APC (Adenomatous Polyposis Coli) germline mutation (APC-HB). This French multicentric retrospective study included 12 APC-HB patients under 5 at diagnosis. Clinical features of APC-HB were compared to the French SIOPEL2-3 cohort of HB patients. Molecular and histopathological analyses of APC-HB were compared to...

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PMID: 31069152
DOI: 10.1080/2162402x.2019.1583547

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