Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline APC mutations in hepatoblastoma

18 Dec 2017

Abstract excerpt

BACKGROUND: Conflicting reports on the frequency of germline adenomatous polyposis coli (APC) gene mutations in patients with hepatoblastoma (HB) have called into question the clinical value of APC mutation testing on apparently sporadic HB. METHODS: An Institutional Review Board approved retrospective review of clinical data collected from patients with HB who received APC testing at our institution was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Genetic factors in colorectal cancer
Share to Hepatocellular Carcinoma Treatment and Prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29251405
DOI: 10.1002/pbc.26892

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline APC mutations in hepatoblastomaPMID 29251405Read ↗

Hepatoblastoma in patients with molecularly proven familial adenomatous polyposis: Clinical characteristics and rationale for surveillance screeningSemantic proximity Read ↗

APC germline hepatoblastomas demonstrate cisplatin-induced intratumor tertiary lymphoid structuresSemantic proximity Read ↗

Hepatoblastoma and APC gene mutation in familial adenomatous polyposis.Semantic proximity Read ↗

The spectrum of APC mutations in children with hepatoblastoma from familial adenomatous polyposis kindreds.Semantic proximity Read ↗

Somatic mutations of the APC gene in sporadic hepatoblastomas.Semantic proximity Read ↗

Familial adenomatous polyposis in two brothers with hepatoblastoma: implications for diagnosis and screening.Semantic proximity Read ↗

Germline APC mutations are not commonly seen in children with sporadic hepatoblastoma.Semantic proximity Read ↗

Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations?Semantic proximity Read ↗

Integrated genotype-phenotype analysis of familial adenomatous polyposis-associated hepatocellular adenomas.Semantic proximity Read ↗

Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene.Semantic proximity Read ↗

Sporadic childhood hepatoblastomas show activation of beta-catenin, mismatch repair defects and p53 mutations.Semantic proximity Read ↗

Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.