Thymic nurse cell rescue of early CD4+CD8+ thymocytes from apoptosis.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Thymic nurse cell rescue of early CD4+CD8+ thymocytes from apoptosis.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Dec 1995

Pezzano M, Li Y, Philp D, Omene C, Cantey M, Saunders G, Guyden J C

Abstract excerpt

We have now developed temperature sensitive lines of thymic nurse cells (TNCs), using the SV40 viral mutant tsA58, that maintain the ability to selectively internalize a subpopulation of alpha beta TCR+CD4+CD8+ thymocytes in vitro. One line, tsTNC-1, was shown to be able to rescue a subset of CD4...

Topics

Animals
Apoptosis
CD4 Antigens
CD8 Antigens
Cell Differentiation
Cell Line
Cell Survival
DNA
Mice
Microscopy, Electron
Microscopy, Electron, Scanning
Mutation
Phenotype
Receptors, Antigen, T-Cell, alpha-beta
Simian virus 40
T-Lymphocyte Subsets
Temperature
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 8747091

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8747091-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics