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Article

Thymic nurse cell rescue of early CD4+CD8+ thymocytes from apoptosis.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Dec 1995

Pezzano M, Li Y, Philp D, Omene C, Cantey M, Saunders G, Guyden J C

Abstract excerpt

We have now developed temperature sensitive lines of thymic nurse cells (TNCs), using the SV40 viral mutant tsA58, that maintain the ability to selectively internalize a subpopulation of alpha beta TCR+CD4+CD8+ thymocytes in vitro. One line, tsTNC-1, was shown to be able to rescue a subset of CD4+CD8+ thymocytes from programmed cell death at 32 degrees C, the temperature at which binding and internalization were...

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Identifiers

PMID: 8747091

Genes

TNC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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