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Article

The immortalization of thymic nurse cells by SV40 virus.

Cellular immunology - 1 Apr 1991

Pezzano M, Li Y, Yang Y M, Guyden J

Abstract excerpt

Thymic nurse cells (TNCs) are stromal elements that contain between 20 and 200 T cells within their cytoplasm. Because of this unique feature they are believed to play a role in thymocyte development. Unfortunately, it has been difficult to obtain pure TNCs in quantities sufficient for extensive evaluation of their thymic function. As a result, only a limited amount of information is available that characterizes...

Topics

Animals
Cell Separation
Cell Transformation, Viral
Mice
Mice, Inbred C57BL
Phenotype
Simian virus 40
T-Lymphocytes
Thymus Gland

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1849801
DOI: 10.1016/0008-8749(91)90116-s

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1849801-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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