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Article

Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selection.

Cellular immunology - 1 Jan 2010

Hendrix Tonya M, Chilukuri Rajendra V E, Martinez Marcia, Olushoga Zachariah, Blake Andrew, Brohi Moazzam, Walker Christopher, Samms Michael, Guyden Jerry C

Abstract excerpt

Thymic nurse cells (TNCs) are epithelial cells in the thymic cortex that contain as many as 50 thymocytes within specialized cytoplasmic vacuoles. The function of this cell-in-cell interaction has created controversy since their discovery in 1980. Further, some skepticism exists about the idea that apoptotic thymocytes within the TNC complex result from negative selection, a process believed to occur exclusively...

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Identifiers

PMID: 20035931
DOI: 10.1016/j.cellimm.2009.11.004
PMCID: PMC2830717

Genes

TNC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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