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Article

Distinct roles of yeast MEC and RAD checkpoint genes in transcriptional induction after DNA damage and implications for function.

1 May 1996

Abstract excerpt

In eukaryotic cells, checkpoint genes cause arrest of cell division when DNA is damaged or when DNA replication is blocked. In this study of budding yeast checkpoint genes, we identify and characterize another role for these checkpoint genes after DNA damage-transcriptional induction of genes. We found that three checkpoint genes (of six genes tested) have strong and distinct roles in transcriptional induction in...

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Identifiers

PMID: 8744945
DOI: 10.1091/mbc.7.5.703

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