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The DNA damage checkpoint: A tale from budding yeast

15 Sept 2022

Abstract excerpt

Studies performed in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have led the way in defining the DNA damage checkpoint and in identifying most of the proteins involved in this regulatory network, which turned out to have structural and functional equivalents in humans. Subsequent experiments revealed that the checkpoint is an elaborate signal transduction pathway that has the ability to...

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PMID: 36186482
DOI: 10.3389/fgene.2022.995163

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