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Article

RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast.

The EMBO journal - 1 Jun 1999

Gardner R, Putnam C W, Weinert T

Abstract excerpt

Eukaryotic checkpoint genes regulate multiple cellular responses to DNA damage. In this report, we examine the roles of budding yeast genes involved in G2/M arrest and tolerance to UV exposure. A current model posits three gene classes: those encoding proteins acting on damaged DNA (e.g. RAD9 and RAD24), those transducing a signal (MEC1, RAD53 and DUN1) or those participating more directly in arrest (PDS1). Here,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10357828
DOI: 10.1093/emboj/18.11.3173
PMCID: PMC1171398

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RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast.PMID 10357828Read ↗

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Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.Semantic proximity Read ↗

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Activation of the budding yeast securin Pds1 but not Rad53 correlates with double-strand break-associated G2/M cell cycle arrest in a mec1 hypomorphic mutant.Semantic proximity Read ↗

Molecular basis of the essential s phase function of the rad53 checkpoint kinase.Semantic proximity Read ↗

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Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.Semantic proximity Read ↗

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