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Article

DNA damage checkpoints and cancer.

Journal of molecular histology - 1 Sept 2006

Shimada Midori, Nakanishi Makoto

Abstract excerpt

DNA damage checkpoint is one of the surveillance systems to maintain genomic integrity. Checkpoint systems sense the DNA damage and execute cell cycle arrest through inhibiting the activity of cell cycle regulators. This pathway is essential for the maintenance of genome stability and prevention of tumor development. Recent studies have showed that the cellular responses towards DNA damage, such as cell cycle...

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Identifiers

PMID: 16841236
DOI: 10.1007/s10735-006-9039-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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