Article
Gene conversion and homologous recombination in murine B cells.
Seminars in immunology - 1 Jun 1996
Selsing E, Xu B, Sigurdardottir D
Abstract excerpt
Gene conversion has been found to be important in the diversification of antibody genes in chickens and in rabbits. In other species, however, it is not clear whether gene conversion plays any role in antibody diversity. Analysis of an H-chain antibody gene construct that was designed to optimize...
Topics
- Animals
- B-Lymphocytes
- Base Sequence
- Gene Conversion
- Genes, Immunoglobulin
- Immunoglobulin Class Switching
- Mice
- Molecular Sequence Data
- Mutation
- Transgenes