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Article

Analysis of sequence transfers resembling gene conversion in a mouse antibody transgene.

Science (New York, N.Y.) - 9 Sept 1994

Xu B, Selsing E

Abstract excerpt

The role of gene conversion in murine immunoglobulin gene diversification is unclear. An antibody gene construct designed to provide the homologous donor and acceptor sequences required for conversion mechanisms was produced and used to generate transgenic mice. When these transgenic mice were immunized, DNA sequence transfers between tandem transgene VDJ regions were detectable and resembled gene conversion...

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Identifiers

PMID: 8079173
DOI: 10.1126/science.8079173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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