Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis.

Neuroscience letters - 12 Apr 1996

Siddons M A, Pickering-Brown S M, Mann D M, Owen F, Cooper P N

Abstract excerpt

Using PCR and restriction digest analysis, the frequencies of the variant cytochrome P450 debrisoquine hydroxylase CYP2D6 alleles CYP2D6(A) and CYP2D6(B) were investigated in 50 patients with amyotrophic lateral sclerosis (ALS) and 13 patients with ALS and frontotemporal dementia (FTD) and compared to those frequencies in patients with FTD alone and Alzheimer's disease (AD). The CYP2D6(T) allelic frequency was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cytochrome P-450 CYP2D6
Share to Cytochrome P-450 Enzyme System

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genotype

Share to Mixed Function Oxygenases

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8731176
DOI: 10.1016/0304-3940(96)12549-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis.PMID 8731176Read ↗

Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population.Semantic proximity Read ↗

Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease.Semantic proximity Read ↗

Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease.Semantic proximity Read ↗

CYP2D6 allelic frequencies in young-onset Parkinson's disease.Semantic proximity Read ↗

Mutation frequencies of the cytochrome CYP2D6 gene in Parkinson disease patients and in families.Semantic proximity Read ↗

Pharmacogenetics of Debrisoquine and its Use as a Marker For CYP2D6 Hydroxylation CapacitySemantic proximity Read ↗

Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis.Semantic proximity Read ↗

Mutant debrisoquine hydroxylation genes in Parkinson's disease.Semantic proximity Read ↗

CYP2D6 variants in amyotrophic lateral sclerosis: an association study of risk and survivalSemantic proximity Read ↗

An association study of debrisoquine hydroxylase (CYP2D6) polymorphisms in schizophrenia.Semantic proximity Read ↗

The CYP2D6B allele is not overrepresented in a population of German patients with idiopathic Parkinson's disease.Semantic proximity Read ↗

Debrisoquine hydroxylase gene polymorphism in familial Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.