CYP2D6 allelic frequencies in young-onset Parkinson's disease.

doi:10.1212/wnl.47.1.225

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Article

CYP2D6 allelic frequencies in young-onset Parkinson's disease.

Neurology - 1 Jul 1996

Sandy M S, Armstrong M, Tanner C M, Daly A K, Di Monte D A, Langston J W, Idle J R

Abstract excerpt

Parkinson's disease (PD) is thought to develop as a result of interactions between genetic susceptibility factors and environmental exposures. One candidate gene is CYP2D6, which codes for the debrisoquine 4-hydroxylase cytochrome P450. Impairment of debrisoquine 4-hydroxylase activity has been a...

Topics

Age of Onset
Aged
Alleles
Base Sequence
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Genotype
Humans
Middle Aged
Mixed Function Oxygenases
Molecular Sequence Data
Parkinson Disease
Risk Factors

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