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Article

CYP2D6 allelic frequencies in young-onset Parkinson's disease.

Neurology - 1 Jul 1996

Sandy M S, Armstrong M, Tanner C M, Daly A K, Di Monte D A, Langston J W, Idle J R

Abstract excerpt

Parkinson's disease (PD) is thought to develop as a result of interactions between genetic susceptibility factors and environmental exposures. One candidate gene is CYP2D6, which codes for the debrisoquine 4-hydroxylase cytochrome P450. Impairment of debrisoquine 4-hydroxylase activity has been associated with an increased risk of PD in patients with younger age at disease onset. Genotyping studies in patients...

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Identifiers

PMID: 8710083
DOI: 10.1212/wnl.47.1.225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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