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Article

A screen for genes that function downstream of Ras1 during Drosophila eye development.

Genetics - 1 May 1996

Karim F D, Chang H C, Therrien M, Wassarman D A, Laverty T, Rubin G M

Abstract excerpt

Cell-fate specification of the R7 photoreceptor cell is controlled by the sevenless receptor tyrosine kinase (SevRTK) and Ras1, the Drosophila homologue of mammalian H-ras, K-ras and N-ras oncogenes. An activated form of Ras1 expressed under control of the sevenless enhancer/promoter (sev-Ras1V12) induces production of supernumerary R7 photoreceptor cells, which causes the eye to become rough in appearance. To...

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Identifiers

PMID: 8722784
DOI: 10.1093/genetics/143.1.315
PMCID: PMC1207264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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