Article
The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination.
Development (Cambridge, England) - 1 Jan 1995
Begemann G, Michon A M, vd Voorn L, Wepf R, Mlodzik M
Abstract excerpt
The Drosophila seven-up (svp) gene specifies outer photoreceptor cell fate in eye development and encodes an orphan nuclear receptor with two isoforms. Transient expression under the sevenless enhancer of either svp isoform leads to a dosage-dependent transformation of cone cells into R7 photorec...
Topics
- Animals
- Cloning, Molecular
- Drosophila
- Embryonic Induction
- Gene Expression
- Gene Expression Regulation, Developmental
- Genes, Insect
- Genes, ras
- Genotype
- Models, Genetic
- Mutation
- Phenotype
- Photoreceptor Cells, Invertebrate
- Signal Transduction