Article
Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.
The EMBO journal - 16 Jan 1995
Hariharan I K, Hu K Q, Asha H, Quintanilla A, Ezzell R M, Settleman J
Abstract excerpt
The rho family of GTPases has been implicated in regulating changes in cell morphology in response to extracellular signals. We have cloned three widely expressed members of this family from Drosophila melanogaster; a rho homologue (Rho1) and two rac homologues (Rac1 and Rac2). Flies harbouring a...
Topics
- Amino Acid Sequence
- Animals
- Animals, Genetically Modified
- Base Sequence
- Cloning, Molecular
- DNA, Complementary
- Drosophila Proteins
- Drosophila melanogaster
- Fungal Proteins
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Gene Expression Regulation, Developmental
- Humans