Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation.

doi:10.1038/355559a0

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Article

Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation.

Nature - 6 Feb 1992

Fortini M E, Simon M A, Rubin G M

Abstract excerpt

Cell-fate specification of R7 photoreceptors in the developing Drosophila eye depends on an inductive signal from neighbouring R8 cells. Mutations in three genes, sevenless (sev), bride-of-sevenless (boss) and seven-in-absentia (sina) cause the R7 precursor to become a non-neural cone cell. The s...

Topics

Animals
Animals, Genetically Modified
Cell Differentiation
Drosophila
Drosophila Proteins
ELAV Proteins
Eye
Eye Proteins
Gene Expression Regulation
Genes, ras
Membrane Glycoproteins
Microscopy, Electron, Scanning
Mutation
Photoreceptor Cells
Receptor Protein-Tyrosine Kinases
Receptors, Cell Surface
Ribonucleoproteins
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 1311054
DOI: 10.1038/355559a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1311054-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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