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Article

Mutations Modulating Raf signaling in Drosophila eye development.

Genetics - 1 Jan 1996

Dickson B J, van der Straten A, Dominguez M, Hafen E

Abstract excerpt

The R7 fate is specified during Drosophila eye development by an inductive signal transduced intracellularly via the Raf kinase. We have performed a genetic screen for dominant mutations that alter the efficiency with which cells respond to a constitutively activated Raf kinase. Such mutations may affect genes involved in signal transduction downstream of Raf. We have isolated 44 mutations that define eight...

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Identifiers

PMID: 8770593
DOI: 10.1093/genetics/142.1.163
PMCID: PMC1206944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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