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Article

Mutations Modulating Raf signaling in Drosophila eye development.

Genetics - 1 Jan 1996

Dickson B J, van der Straten A, Dominguez M, Hafen E

Abstract excerpt

The R7 fate is specified during Drosophila eye development by an inductive signal transduced intracellularly via the Raf kinase. We have performed a genetic screen for dominant mutations that alter the efficiency with which cells respond to a constitutively activated Raf kinase. Such mutations ma...

Topics

Alleles
Animals
Chromosome Mapping
Drosophila
Eye
Female
Genes, Insect
Genetic Complementation Test
Homozygote
Male
Microscopy, Electron, Scanning
Phenotype
Protein Serine-Threonine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins

Proto-Oncogene Proteins c-raf

Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 8770593
DOI: 10.1093/genetics/142.1.163
PMCID: PMC1206944

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8770593-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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