Article
Genetic variability of the CYP 2D6 gene is not a risk factor for sporadic Parkinson's disease.
Annals of neurology - 1 Sept 1996
Diederich N, Hilger C, Goetz C G, Keipes M, Hentges F, Vieregge P, Metz H
Abstract excerpt
Genetic studies of the frequencies of mutant alleles for coding cytochrome P-450 monooxygenase (CYP 2D6) in Parkinson's disease (PD) patients have been inconsistent. We studied the mutants A and B in 80 strictly defined sporadic PD patients divided into young age onset of the disease (< 40 years, N = 20), mid age onset (40-50 years, N = 12), and older age onset (> 50 years, N = 48). They were compared with 108...
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