Article
APOE, vascular pathology, and the AD brain.
Neurology - 26 Jul 2005
Yip A G, McKee A C, Green R C, Wells J, Young H, Cupples L A, Farrer L A
Abstract excerpt
OBJECTIVE: To use neuropathologic data to examine the association between APOE genotype and cerebrovascular lesions commonly found in Alzheimer disease (AD), as well as neuritic senile plaque (SP) and neurofibrillary tangle (NFT) burden. METHODS: The sample comprised brains from 96 men and 3 women who fulfilled NIA-Reagan criteria for intermediate to high likelihood of AD. Region-specific and global measures of...
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