Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy.

doi:10.1002/ana.410380219

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Article

Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy.

Annals of neurology - 1 Aug 1995

Greenberg S M, Rebeck G W, Vonsattel J P, Gomez-Isla T, Hyman B T

Abstract excerpt

Cerebral amyloid angiopathy (CAA) is characterized by cerebrovascular deposition of the amyloid beta-peptide, leading to intracerebral hemorrhage in severe cases. Other than rare familial cases, the only identified risks for CAA are advancing age and accompanying Alzheimer's disease. We tested wh...

Topics

Alleles
Apolipoprotein E4
Apolipoproteins E
Base Sequence
Cerebral Amyloid Angiopathy
Cerebral Hemorrhage
Dementia
Genotype
Humans
Middle Aged
Molecular Sequence Data

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