Article
Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy.
Annals of neurology - 1 Aug 1995
Greenberg S M, Rebeck G W, Vonsattel J P, Gomez-Isla T, Hyman B T
Abstract excerpt
Cerebral amyloid angiopathy (CAA) is characterized by cerebrovascular deposition of the amyloid beta-peptide, leading to intracerebral hemorrhage in severe cases. Other than rare familial cases, the only identified risks for CAA are advancing age and accompanying Alzheimer's disease. We tested whether the apolipoprotein E epsilon 4 (apoE epsilon 4) allele was associated with CAA and hemorrhage and whether this...
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