Article
[Protein p53 inhibits the activity of the enhancer of the immediate-early genes of murine cytomegalovirus].
Giornale di batteriologia, virologia ed immunologia - 1 Jan 2000
Lembo D, Angeretti A, Cavallo R, Gariglio M, Gribaudo G, Landolfo S
Abstract excerpt
The protein encoded by the tumor suppressor gene p53 can complex and functionally interact with cytomegalovirus proteins produced during the immediate-early phase of infection. The functions of these complex are unclear but there is some evidence to suggest that binding of p53 to these viral prot...
Topics
- 3T3 Cells
- Animals
- Cell Line, Transformed
- Genes, Immediate-Early
- Genes, ras
- Genetic Vectors
- Humans
- Immediate-Early Proteins
- Mice
- Muromegalovirus
- Mutation
- Promoter Regions, Genetic
