Article
[Protein p53 inhibits the activity of the enhancer of the immediate-early genes of murine cytomegalovirus].
Giornale di batteriologia, virologia ed immunologia - 1 Jan 2000
Lembo D, Angeretti A, Cavallo R, Gariglio M, Gribaudo G, Landolfo S
Abstract excerpt
The protein encoded by the tumor suppressor gene p53 can complex and functionally interact with cytomegalovirus proteins produced during the immediate-early phase of infection. The functions of these complex are unclear but there is some evidence to suggest that binding of p53 to these viral proteins may inactivate p53 functions. Recent reports have shown that p53 is involved in regulation of transcription. In...
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