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Article

Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells.

Journal of virology - 1 Oct 1992

Deb S, Jackson C T, Subler M A, Martin D W

Abstract excerpt

Wild-type p53 has recently been shown to repress transcription from several cellular and viral promoters. Since p53 mutations are the most frequently reported genetic defects in human cancers, it becomes important to study the effects of mutations of p53 on promoter functions. We, therefore, have studied the effects of wild-type and mutant human p53 on the human proliferating-cell nuclear antigen (PCNA) promoter...

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Identifiers

PMID: 1356162
DOI: 10.1128/JVI.66.10.6164-6170.1992
PMCID: PMC283665

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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