Wild-type mouse p53 down-regulates transcription from different virus enhancer/promoters.

Article

Wild-type mouse p53 down-regulates transcription from different virus enhancer/promoters.

Oncogene - 1 Mar 1993

Jackson P, Bos E, Braithwaite A W

Abstract excerpt

The protein encoded by the tumour-suppressor gene p53 can complex with SV40 virus large T antigen, the adenovirus E1B 58-kDa protein and the E6 protein of human papillomavirus type 16. The functions of these complexes are unclear, but there is some evidence to suggest that binding of p53 to these...

Topics

Animals
Creatine Kinase
Cytomegalovirus
Down-Regulation
Enhancer Elements, Genetic
Genes, Viral
Genes, p53
Humans
Mice
Mutation
Promoter Regions, Genetic
Simian virus 40
Transcription, Genetic

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