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Article

Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression.

Cell - 26 Jul 1996

Connelly C, Hieter P

Abstract excerpt

The budding yeast SKP1 gene, identified as a dosage suppressor of a known kinetochore protein mutant, encodes an intrinsic 22.3 kDa subunit of CBF3, a multiprotein complex that binds centromere DNA in vitro. Temperature-sensitive mutations in SKP1 define two distinct phenotypic classes. skp1-4 mutants arrest predominantly as large budded cells with a G2 DNA content and short mitotic spindle, consistent with a...

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Identifiers

PMID: 8706132
DOI: 10.1016/s0092-8674(00)80099-9
PMCID: PMC7125826

Genes

SKP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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