Article
Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression.
Cell - 26 Jul 1996
Connelly C, Hieter P
Abstract excerpt
The budding yeast SKP1 gene, identified as a dosage suppressor of a known kinetochore protein mutant, encodes an intrinsic 22.3 kDa subunit of CBF3, a multiprotein complex that binds centromere DNA in vitro. Temperature-sensitive mutations in SKP1 define two distinct phenotypic classes. skp1-4 mu...
Topics
- Alleles
- Base Sequence
- Biological Evolution
- Cell Cycle
- Cell Cycle Proteins
- Conserved Sequence
- DNA-Binding Proteins
- Fungal Proteins
- Gene Dosage
- Gene Expression
- Kinetochores
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- S-Phase Kinase-Associated Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid