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Article

Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.

Molecular biology of the cell - 1 Jun 1997

Geiser J R, Schott E J, Kingsbury T J, Cole N B, Totis L J, Bhattacharyya G, He L, Hoyt M A

Abstract excerpt

Kinesin-related Cin8p is the most important spindle-pole-separating motor in Saccharomyces cerevisiae but is not essential for cell viability. We identified 20 genes whose products are specifically required by cell deficient for Cin8p. All are associated with mitotic roles and represent at least four different functional pathways. These include genes whose products act in two spindle motor pathways that overlap...

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Identifiers

PMID: 9201714
DOI: 10.1091/mbc.8.6.1035
PMCID: PMC305712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.PMID 9201714Read ↗

Kinesin-related proteins required for assembly of the mitotic spindle.Semantic proximity Read ↗

Mitotic motors in Saccharomyces cerevisiae.Semantic proximity Read ↗

Analysis of kinesin motor function at budding yeast kinetochores.Semantic proximity Read ↗

Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins.Semantic proximity Read ↗

Homotetrameric form of Cin8p, a Saccharomyces cerevisiae kinesin-5 motor, is essential for its in vivo function.Semantic proximity Read ↗

Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.Semantic proximity Read ↗

Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.Semantic proximity Read ↗

Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation.Semantic proximity Read ↗

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

The Saccharomyces cerevisiae homolog of p24 is essential for maintaining the association of p150Glued with the dynactin complex.Semantic proximity Read ↗

Mid-anaphase arrest in S. cerevisiae cells eliminated for the function of Cin8 and dynein.Semantic proximity Read ↗

Mutations affecting spindle pole body and mitotic exit network function are synthetically lethal with a deletion of the nucleoporin NUP1 in S. cerevisiae.Semantic proximity Read ↗

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