Article
MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase 3.
Molecular and cellular biology - 1 Jan 1994
Puziss J W, Hardy T A, Johnson R B, Roach P J, Hieter P
Abstract excerpt
The yeast gene MCK1 encodes a serine/threonine protein kinase that is thought to function in regulating kinetochore activity and entry into meiosis. Disruption of MCK1 confers a cold-sensitive phenotype, a temperature-sensitive phenotype, and sensitivity to the microtubule-destabilizing drug beno...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Calcium-Calmodulin-Dependent Protein Kinases
- Cold Temperature
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Genes, Suppressor
- Glycogen Synthase Kinase 3
- Glycogen Synthase Kinases
- Microtubule-Associated Proteins
- Molecular Sequence Data
- Mutation