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Article

Genetic evidence for a role of phospholipase C at the budding yeast kinetochore.

Molecular genetics and genomics : MGG - 1 May 2003

DeLillo N, Romero C, Lin H, Vancura A

Abstract excerpt

Chromosome segregation during mitosis requires kinetochores, specialized organelles that mediate chromosome attachment to spindle microtubules. We have shown previously that in budding yeast, Plc1p (phosphoinositide-specific phospholipase C) localizes to centromeric loci, associates with the kinetochore proteins Ndc10p and Cep3p, and affects the function of kinetochores. Deletion of PLC1 results in nocodazole...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12756538
DOI: 10.1007/s00438-003-0832-4

Genes

BUB1
BUB3
SKP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic evidence for a role of phospholipase C at the budding yeast kinetochore.PMID 12756538Read ↗

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