Article
An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor.
Cell - 26 Jul 1996
Shaham S, Horvitz H R
Abstract excerpt
The C. elegans gene ced-4 is essential for programmed cell death. We report that ced-4 encodes two transcripts and that whereas the major transcript can cause programmed cell death, the minor transcript can act oppositely and prevent programmed cell death, thus defining a novel class of cell death inhibitors. That ced-4 has both cell-killing and cell-protective functions is consistent with previous genetic...
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