Article
An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor.
Cell - 26 Jul 1996
Shaham S, Horvitz H R
Abstract excerpt
The C. elegans gene ced-4 is essential for programmed cell death. We report that ced-4 encodes two transcripts and that whereas the major transcript can cause programmed cell death, the minor transcript can act oppositely and prevent programmed cell death, thus defining a novel class of cell deat...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Apoptosis
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Calcium-Binding Proteins
- Conserved Sequence
- Exons
- Gene Expression Regulation
- Genes, Helminth