Article
Allele loss on chromosome arm 6q and fine mapping of the region at 6q27 in epithelial ovarian cancer.
Genes, chromosomes & cancer - 1 Apr 1996
Cooke I E, Shelling A N, Le Meuth V G, Charnock M L, Ganesan T S
Abstract excerpt
Genetic changes have been shown to be important in determining the multistep progression of cancer. Allele loss studies and karyotypic analysis of epithelial ovarian tumours have indicated the presence of putative tumour suppressor genes on chromosomes 6, 11, 13, 17, 18, 22, and X. We have focused on chromosome arm 6q to identify the minimal region that may contain a putative tumour suppressor gene. Nineteen...
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