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Article

Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma.

Cancer research - 15 Oct 1991

Millikin D, Meese E, Vogelstein B, Witkowski C, Trent J

Abstract excerpt

Malignant melanoma has been documented to display recurring abnormalities of chromosome 6, particularly the long arm (6q). Restriction fragment length polymorphism analysis was used as a molecular genetic approach to examine loci on chromosome 6q for loss of constitutional heterozygosity (LOH). Five DNA markers that recognize restriction fragment length polymorphisms along 6q and one polymorphic DNA marker for 6p...

Topics

Alleles
Chromosomes, Human, Pair 6
Genetic Testing
Heterozygote
Humans
Melanoma
Polymorphism, Restriction Fragment Length

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1680551

Genes

MYB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1680551-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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