Article
Multiple regions of allelic loss from chromosome arm 6q in malignant mesothelioma.
Cancer research - 15 Sept 1997
Bell D W, Jhanwar S C, Testa J R
Abstract excerpt
Our previous cytogenetic studies of malignant mesotheliomas (MMs) revealed losses from 6q15-21 in approximately 40% of cases, suggestive of recurrent loss of function of a putative tumor suppressor gene(s) located in this chromosome region. To more precisely define the critical region of molecular genetic loss within 6q, we have constructed a high-resolution deletion map of this chromosome arm in 46 MMs. We...
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