Article
Human epithelial ovarian cancer allelotype.
Cancer research - 15 May 1993
Cliby W, Ritland S, Hartmann L, Dodson M, Halling K C, Keeney G, Podratz K C, Jenkins R B
Abstract excerpt
To determine which chromosomes and chromosomal regions contain putative tumor suppressor genes important for human epithelial ovarian cancer, we performed loss of heterozygosity (LOH) studies on 37 primary epithelial ovarian tumors. Using 70 polymorphic markers, we examined all chromosome arms (excluding acrocentric arms) on all specimens. Our findings show a high frequency of LOH for the following chromosome...
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