Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas.

Cancer research - 1 May 1990

Lee J H, Kavanagh J J, Wildrick D M, Wharton J T, Blick M

Abstract excerpt

Recently, tumor-specific allele loss has been shown to be an important characteristic of some tumors. When such loss includes one or more growth-regulatory genes, it may allow the expression of tumorigenicity. Using Southern blots, we analyzed normal and tumor DNA samples from 19 ovarian cancer patients, using a series of polymorphic DNA probes that map to a variety of chromosomal loci. Of 14 informative cases,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Aberrations
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 17

Share to Chromosomes, Human, Pair 6

Share to Heterozygote

Share to Ovarian Neoplasms

Share to Receptors, Estrogen

Source

Identifiers

PMID: 2328498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas.PMID 2328498Read ↗

Molecular genetic changes in human epithelial ovarian malignancies.Semantic proximity Read ↗

Human epithelial ovarian cancer allelotype.Semantic proximity Read ↗

Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.Semantic proximity Read ↗

Allele loss on chromosome arm 6q and fine mapping of the region at 6q27 in epithelial ovarian cancer.Semantic proximity Read ↗

Allelotype of human ovarian cancer.Semantic proximity Read ↗

Whole genome amplification and high-throughput allelotyping identified five distinct deletion regions on chromosomes 5 and 6 in microdissected early-stage ovarian tumors.Semantic proximity Read ↗

Loss of constitutional heterozygosity on chromosome 11p in human ovarian cancer. Positive correlation with grade of differentiation.Semantic proximity Read ↗

Loss of heterozygosity on the long arm of chromosome 6 in breast cancer: possibly four regions of deletion.Semantic proximity Read ↗

A study of chromosome 6 allele loss in human colorectal carcinomas.Semantic proximity Read ↗

Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors.Semantic proximity Read ↗

Allelic loss at chromosome band 6q14 correlates with favorable prognosis in hepatocellular carcinoma.Semantic proximity Read ↗

Study of allelic losses on 3p, 6q, and 17p in human urothelial cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.