Article
Detailed deletion mapping of chromosome 6q in borderline epithelial ovarian tumors.
Cancer research - 15 May 1995
Rodabaugh K J, Blanchard G, Welch W R, Bell D A, Berkowitz R S, Mok S C
Abstract excerpt
We have used PCR amplification of tandem repeats and Southern blot analysis to study the pattern of allelic loss at chromosome 6q in borderline ovarian tumors and compared that with invasive ovarian carcinomas. DNA from 46 borderline ovarian tissues, 20 invasive ovarian tumor tissues, together with corresponding uninvolved (control) tissues was used. The invasive tumors demonstrated the highest percentage of loss...
Topics
- Alleles
- Blotting, Southern
- Chromosomes, Human, Pair 6
- Female
- Gene Deletion
- Humans
- Ovarian Neoplasms
- Polymerase Chain Reaction
