Article
A study of chromosome 6 allele loss in human colorectal carcinomas.
Anticancer research - 1 Jan 2000
Wildrick D M, Alfaro S R, Gope R, Boman B M
Abstract excerpt
Matched normal/tumor DNA pairs from patients with sporadic and hereditary (FAP = familial adenomatous polyposis) colorectal carcinoma were examined for tumor-specific allele loss on chromosome 6 using cDNA probes for the avian myeloblastosis viral oncogene homologue (MYB on 6q22-q23), the estroge...
Topics
- Adenomatous Polyposis Coli
- Alleles
- Blotting, Southern
- Chorionic Gonadotropin
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- Colonic Neoplasms
- DNA Probes
- DNA, Neoplasm
- Humans
- Oncogenes
- Receptors, Estrogen
- Rectal Neoplasms