Article
Proximal 6q, a region showing allele loss in primary breast cancer.
British journal of cancer - 1 Feb 1995
Orphanos V, McGown G, Hey Y, Boyle J M, Santibanez-Koref M
Abstract excerpt
To define regions of deletion of chromosome 6q in breast cancer, we scored 18 (CA)n microsatellites for allelic imbalance (AI) in 42 paired blood/tumour samples. Heterozygosity frequencies of the markers in the sample population ranged from 31% to 92% (mean 68%). Two regions of the chromosome arm showed AI values greater than the background range of 10-22% (mean 17%) of informative cases that was observed with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
